Production Of Transgenic Animals Notes

Transgenic animals are created-To study how genes are regulated and how they affect the normal functions of the body and its development.

Production of transgenic animals notes. Transgenic animals have the potential of agricultural applications like improved growth rate and carcass composition improved resistance to disease increased milk. The foreign gene is constructed using recombinant DNA methodology. Applications Of Transgenic Animals.

Benefits of Transgenic Animals The benefits of these animals to human welfare can be grouped into areas. Transgene is incorporated into the ES cell by Microinjection By a retro virus By electroporation Transgenic stem cells are grown in vitro. Agricultural Applications a Breeding Farmers have always used selective breeding to produce animals that exhibit desired traits eg.

Animals that have had their DNA manipulated to possess and express a foreign gene are known as transgenic animals. Theses mechanism is absent in cell culture. ES cells are obtained from the inner cell mass of a blastocyst.

The three main ways of producing transgenic animals are pronuclear manipulation embryonic stem ES cell manipulation and. The first transgenic animal was produced is mice by injecting DNA to mouse embryos then implanting the embryos in female mice. One favoured method involves the inoculation of the DNA into the pronucleus of a fertilised ovum followed by implantation into pseudo pregnant females.

Many procedures have been developed to increase the efficiency of this generally inefficient process. Transgenic animal technologies have come a long way since the creation of the first transgenic mouse in 1974 Transgenic Mouse 2005. Advantages of Transgenic Animals.

A transgenic animal is an animal in which one or more genes have been introduced into its nonreproductive cells. The transgenic animals are created because of the benefits they provide to the man. PowerPoint PPT presentation.